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R & D

SungenBio is dedicated in R&D with technological accumulation, and takes the advance of technology and production as it's motivation of progress. A center of biotech R&D has been set up. There are more than 30 experts with multidisciplinary, including PH. D., master, engineer, licensed pharmacist, etc.. The center comprises of Fermentation Engineering Center , Down Stream Techniques Center, Innovated Drug Screening Center, and Drug Delivery System Center. In order to take advantage of research capability of academic institutions, SungenBio has established a Joint-lab of Secondary Metabolic Engineering cooperated with Institute of Botany , the Chinese Academy of Sciences. And a Joint Research Center of Traditional Chinese Medicine Modernization with School of Traditional Chinese Pharmacy, China Pharmaceutical University has been founded.

1).Fermentation Engineering Center: We have breaded the high-productive strains of veterinary medicines (Enramycin, Doramycin and Nosiheptide) and anti-cancer medicines (Fungxol® Paclitaxel, Fungxotere® Docetaxel, AlternolTM, Bisphenazine-1-Carboxamides and Bisphenazine-1-carboxylic Acid) by fermentation engineering technology. Among those, the anti-cancer medicine Paclitaxel by fungi fermentation has been applied China patent No.:CN1724643, Worldwide PCT patent No.:WO2006/009518 A1, and US patent No.: US20070218531 under publication.

2).Down Stream Techniques Center: Study on the extraction and purification process, membrane separation technology, adsorption and separation by macroporous adsorbing resin to purification and separation, separation by cation exchange resin, supercritical CO2 extraction, etc. and apply to the production line for botanic extracts and separation and purification of fermented products with assurance of high quality.
  

3).Innovated Drug Screening Center: Focus on screening of innovated drugs in vitro and in vivo.
  

4).Innovated Drug Delivery System Center: Study on delivery systems of innovated drugs to increase availability and safety by oral administration, transdermal delivery systems, injectable drug delivery, etc. There are a nano-formulations of anti-cancer medicines project with ShenYang Pharmaceutical University and a nano-formulations by oral administration of protein drug project with Peking University


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